Last Updated：2025/11/30

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A triazolone, derived from resorcinol, that inhibits an oncogenic molecular chaperone

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ganetespib

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Source Word

ganetespib

Noun

uncountable

A triazolone, derived from resorcinol, that inhibits an oncogenic molecular chaperone

Japanese Meaning

レゾルシノール由来のトリアゾロン系化合物で、腫瘍性分子シャペロンを阻害する作用を持つ

What is this buttons?

In an early-phase study, ganetespib demonstrated promising antitumor activity in patients with cancers reliant on the oncogenic chaperone HSP90.

Google Translation / DeepL Translation

初期臨床試験で、発がん性の分子シャペロンを阻害するレゾルシノール由来のトリアゾロンは、HSP90依存性のがん患者において有望な抗腫瘍効果を示した。

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Sense（1）

A triazolone, derived from resorcinol, that inhibits an oncogenic molecular chaperone

In this report, we compare the relative interaction strength of both HSP90α and HSP90β with the transcription factors HSF1 and HIF1α, the kinases ERBB2 and MET, the E3-ubiquitin ligases KEAP1 and RHOBTB2, and the HSP90 inhibitors geldanamycin and ganetespib.

Google Translation / DeepL Translation

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ganetespib

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ganetespib

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