knotty

I could a Tale vnfold, vvhoſe lighteſt vvord / VVould harrovv vp thy ſoule, freeze thy young blood, / Make thy tvvo eyes like Starres, ſtart from their Spheres, / Thy knotty and combined locks to part, / And each particular haire to ſtand an end, / Like Quilles vpon the fretfull Porpentine: […]

In the First Quarto (1603) of the work, the corresponding phrase is “Thy knotted and combined locks to part”.

a knotty pine

a knotty problem

[A] witte in youth, that is not ouer dulle, heauie, knottie and lumpiſhe, but hard, rough, and though ſomwhat ſtaffiſhe, […] ſuch a witte I ſay, if it be, at the firſt well handled by the mother, and rightlie ſmothed and wrought as it ſhould, not ouerwhartlie, and against the wood, by the ſcholemaſter, both for learning, and hole courſe of liuing, proueth alwaies the beſt.