Last Updated：2025/11/20

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(informal, derogatory) A mentally unbalanced, unpredictable person, especially one who displays aggressive behavior.

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headcase

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Source Word

headcase

Noun

derogatory informal

(informal, derogatory) A mentally unbalanced, unpredictable person, especially one who displays aggressive behavior.

Japanese Meaning

（口語、軽蔑的な表現）精神的に不安定で予測不能な人、特に攻撃的な行動を示す人

What is this buttons?

When the headcase in the meeting slammed their fist on the table, everyone fell silent.

Google Translation / DeepL Translation

会議で精神的に不安定な人が拳で机を叩くと、皆が黙り込んだ。

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Sense（1）

(informal, derogatory) A mentally unbalanced, unpredictable person, especially one who displays aggressive behavior.

"A stockbroker doesn't have 80,000 people sitting behind him just waiting for a mistake," says Jim Fassel, whom fans serenaded with "Fire Fassel!" chants during his final weeks as head coach of the New York Giants last season. "It can drive you crazy." From head coach to head case in three easy steps.

Google Translation / DeepL Translation

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Sense（2）

(genetics) A genetic sequence that inhibits terminal branching of the trachea and regulates dendrite pruning.

Another gene downstream of EcR/Usp is headcase. Screening genes that show genetic interactions with EcR mutants, Loncle and Williams identified headcase as a regulator of dendrite pruning (Loncle and Williams 2012).

Google Translation / DeepL Translation

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headcases

（ plural ）

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headcase

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