Last Updated：2025/11/20
(pathology, Britain) A severe hereditary form of anaemia, mainly affecting people of African origin, in which mutated haemoglobin distorts red blood cells into a crescent shape, causing the cells to become stuck in capillaries. Downstream tissues are thus deprived of oxygen causing ischaemia and infarction.
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sickle cell anaemia
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Source Word
sickle cell anaemia
Noun
Britain
uncountable
(pathology,
Britain)
A
severe
hereditary
form
of
anaemia,
mainly
affecting
people
of
African
origin,
in
which
mutated
haemoglobin
distorts
red
blood
cells
into
a
crescent
shape,
causing
the
cells
to
become
stuck
in
capillaries.
Downstream
tissues
are
thus
deprived
of
oxygen
causing
ischaemia
and
infarction.
Japanese Meaning
鎌状赤血球性貧血：主にアフリカ系の人々に起こる重度の遺伝性貧血で、変異したヘモグロビンによって赤血球が三日月形に変形し、毛細血管に詰まることで下流の組織が酸素不足となり、虚血や壊死を引き起こす。
Sense（1）
(pathology,
Britain)
A
severe
hereditary
form
of
anaemia,
mainly
affecting
people
of
African
origin,
in
which
mutated
haemoglobin
distorts
red
blood
cells
into
a
crescent
shape,
causing
the
cells
to
become
stuck
in
capillaries.
Downstream
tissues
are
thus
deprived
of
oxygen
causing
ischaemia
and
infarction.
