(transitive, poetic or in certain phrases) To physically raise or lift. / (transitive, colloquial) To increase the level or amount of. / (transitive, colloquial) To promote.

(uncountable) The direction opposed to the pull of gravity. / (countable) A positive thing, or a time or situation when things are going well. / (particle physics) An up quark.

Away from the surface of the Earth or other planet; in opposite direction to the downward pull of gravity. / To or at a physically higher or more elevated position.

Toward the top of. / Toward the center, source, or main point of reference; toward the end at which something is attached. / From south to north of. / Further along (in any direction).

Facing upwards. / On or at a physically higher level. / Headed or designated to go upward (as an escalator, stairway, elevator etc.) or toward (as a run-up).

(idiomatic, colloquial) Well-informed concerning.

Initialism of Upper Peninsula. / (religion) Initialism of United Presbyterian. / (India) Initialism of Uttar Pradesh. / (software) Initialism of Unified Process.

Initialism of unqualified prospect. / Initialism of university press.

(tennis) Of the ball, having bounced twice. Usually called by the umpire in situations where it is unclear if the ball has bounced a second time to indicate to the players and spectators that the point is over.

(idiomatic) To desist from saying something unless one is able to prove it; to act in a manner that makes further talk unnecessary.