(chemistry) A palladium-catalysed substitution reaction involving a substrate that contains a leaving group in an allylic position. The palladium catalyst first coordinates with the allyl group and then undergoes oxidative addition, forming the π-allyl complex. This allyl complex can then be attacked by a nucleophile, resulting in the substituted product.

Synonym of Sonogashira coupling

plural of Sonogashira reaction

plural of Tsuji-Trost reaction

(chemistry) The reaction of an unsaturated halide (or triflate) with an alkene in the presence of a base and a palladium catalyst to form a substituted alkene.

plural of Heck reaction

plural of Friedel-Crafts reaction

Synonym of hunting reaction

plural of Lewis reaction

A process of alternating vasoconstriction and vasodilation in extremities exposed to cold.