plural of U

(euphemistic) To use the restroom. / (euphemistic) To defecate or urinate, regardless of whether one is in a restroom.

Currently being used. / (archaic) Used; accustomed.

(colloquial, usually with a following present participle or infinitive expression) Used to indicate that the specified action cannot succeed or offers no advantage if successful

(colloquial, usually with a following present participle or infinitive expression) Used to indicate that the specified action cannot succeed or offers no advantage if successful

Bad, cruel or unkind treatment.

To treat someone badly, cruelly or unkindly.

(US) The semi-official use of a drug that has not yet gained official approval in cases where no other treatment is possible

plural of fair use

Worn out; depleted; exhausted; having nothing left; useless, due to the expenditure of all resources.