When the project takes a turn for the worse, the manager desponds and withdraws from the team.

Desponding over the unexpected rejection, he withdrew from the project to gather his thoughts.

His desponding after the failure lasted for weeks, affecting everyone around him.

After three rejections, she desponded and considered giving up her dream.

The desponding news of the company's bankruptcy spread quickly through the office.

The poet wrote about the city's hidden despondings, the small griefs no one dared to mention.

After weeks of searching for inspiration, she found herself stuck in a slough of despond that made every step feel heavier.

After receiving the rejection letters, he felt as if he were wading through sloughs of despond, each step heavier than the last.