(medicine) The primary or major symptom by which a diagnosis is made / (homeopathy) The particular symptom which is regarded most important for choosing the curing substance

Alternative spelling of cardinal-nephew

Any cardinal created by the nepotism of a Pope

(singular only) The position of the Secretarius Papae et superintendens status ecclesiasticæ in the sixteenth- and seventeenth-century Holy See. / (countable) Any officeholder of that position.

A fundamental rule, upon which other matters hinge.

Any of the four principal compass directions: north, south, east and west.

plural of cardinal numeral

plural of cardinal number

(grammar) A word used to represent a cardinal number.

A cardinal of the Roman Catholic Church who is bishop of one of the cardinal ("hinge") dioceses of the Province of Rome. / (more loosely) A cardinal who is a bishop anywhere.