To endure an unpleasant obligation, especially a punishment. / Used other than figuratively or idiomatically: see take, medicine.

(transitive with against or for) Prepare to fight; to arm oneself.

To evaluate something in terms of its expected long-term results rather than its immediate state.

(idiomatic) Alternative form of cross to bear

(chiefly UK, figuratively) To accept both the positive and negative elements in a situation.

(UK, politics) To vacate one's seat in the House of Commons (since resignation is not permitted), under the legal fiction of being appointed to an "office of profit under the Crown": the ancient office of Crown Steward for the Chiltern Hundreds, in modern times a mere sinecure.

(idiomatic) to take priority

To take it from scratch, to take it from the beginning.

(US, informal) To travel on an airplane all night.

(informal) Synonym of take the weight off one's feet